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VRTXVertex Pharmaceuticals

Health care · Pharmaceuticals · Nasdaq

We are a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases, with a focus on specialty markets. 10-K, Item 1

Employees
6,400
Headquarters
Boston, MA
CEO
Reshma Kewalramani
Next results
around Feb 11, 2027
Compare with peers → Embed

What VRTX's directors and officers said they would sell, before they sold: trading plans the company reports each quarter, and the Form 144 notices sellers file on the day of a planned sale. Facts only; most of these sales are routine, such as selling shares from vesting stock awards.

Trading plans adopted or ended

12 plans still running: Alan Garber, Bruce Sachs, Joy Liu, Nancy Thornberry, Sangeeta Bhatia, Charles F. Wagner, Jr., Carmen Bozic, Kristen Ambrose, Jeffrey Leiden, Reshma Kewalramani, Duncan McKechnie.

InsiderWhatDateSharesRuns toReported in
Alan Garber
Director
Adopted 10b5-1 plan Aug 27, 2026 up to 5,320 Jul 30, 2027 10-Q Nov 3, 2026
Bruce Sachs
Director
Adopted 10b5-1 plan Aug 26, 2026 up to 9,888 Jul 20, 2027 10-Q Nov 3, 2026
Joy Liu
EVP, Chief Legal Officer
Adopted 10b5-1 plan Aug 21, 2026 up to 20,764 May 3, 2027 10-Q Nov 3, 2026
Nancy Thornberry
Director
Adopted 10b5-1 plan Aug 15, 2026 up to 2,571 Jul 30, 2027 10-Q Nov 3, 2026
Sangeeta Bhatia
Director
Adopted 10b5-1 plan Aug 13, 2026 up to 1,189 Jul 30, 2027 10-Q Nov 3, 2026
Charles F. Wagner, Jr.
EVP, Chief Operating & Financial Officer
Adopted 10b5-1 plan Aug 10, 2026 up to 15,286 Jul 30, 2027 10-Q Nov 3, 2026
Carmen Bozic
EVP, Global Medicines Development and Medical Affairs, and Chief Medical Officer
Adopted 10b5-1 plan Aug 6, 2026 up to 16,915 Jul 30, 2027 10-Q Nov 3, 2026
Kristen Ambrose
SVP, Chief Accounting Officer
Adopted 10b5-1 plan Aug 6, 2026 up to 5,422 Apr 30, 2027 10-Q Nov 3, 2026
Jeffrey Leiden
Executive Chairman
Adopted 10b5-1 plan Aug 5, 2026 up to 18,411 Nov 4, 2027 10-Q Nov 3, 2026
Reshma Kewalramani
Chief Executive Officer and President, Director
Adopted 10b5-1 plan Aug 5, 2026 up to 47,800 Dec 1, 2027 10-Q Nov 3, 2026
Duncan McKechnie
EVP, Chief Commercial Officer
Adopted 10b5-1 plan Nov 25, 2025 up to 17,367 Nov 13, 2026 10-K Feb 13, 2026
Carmen Bozic
EVP, Global Medicines Development and Medical Affairs, Chief Medical Officer
Adopted 10b5-1 plan Nov 20, 2025 up to 34,733 Nov 2, 2026 10-K Feb 13, 2026
Amit Sachdev
EVP, Chief Patient and External Affairs Officer
Adopted 10b5-1 plan Nov 18, 2025 up to 70,498 Oct 30, 2026 10-K Feb 13, 2026
Reshma Kewalramani
Chief Executive Officer and President
Adopted 10b5-1 plan Nov 17, 2025 up to 40,000 Nov 16, 2026 10-K Feb 13, 2026
Ourania "Nia" Tatsis
EVP, Chief Regulatory and Quality Officer
Adopted 10b5-1 plan Aug 21, 2025 up to 24,301 Jul 31, 2026 10-Q Nov 4, 2025
E. Morrow "Morrey" Atkinson, III
EVP, Chief Technical Operations Officer, Head of Biopharmaceuitcal Sciences and Manufacturing Operations
Adopted 10b5-1 plan Aug 11, 2025 up to 12,709 Apr 30, 2026 10-Q Nov 4, 2025
Kristen Ambrose
SVP, Chief Accounting Officer
Adopted 10b5-1 plan Aug 8, 2025 up to 7,539 Aug 3, 2026 10-Q Nov 4, 2025
Jeffrey Leiden
Executive Chairman
Adopted 10b5-1 plan Aug 6, 2025 up to 144,644 Jan 21, 2026 10-Q Nov 4, 2025
Carmen Bozic
EVP, Global Medicines Development and Medical Affairs, Chief Medical Officer
Adopted 10b5-1 plan May 30, 2025 up to 19,404 Nov 21, 2025 10-Q Nov 4, 2025
Sangeeta Bhatia
Director
Adopted 10b5-1 plan May 27, 2025 up to 1,116 May 8, 2026 10-Q Aug 5, 2025
Charles F. Wagner, Jr.
EVP, Chief Operating & Financial Officer
Adopted 10b5-1 plan May 9, 2025 up to 23,532 Feb 6, 2026 10-Q Aug 5, 2025
Jonathan Biller
EVP, Chief Legal Officer
Adopted 10b5-1 plan Feb 24, 2025 up to 22,217 Feb 27, 2026 10-Q May 6, 2025
Amit Sachdev
EVP, Chief Patient and External Affairs Officer
Adopted 10b5-1 plan Feb 21, 2025 up to 48,505 Jan 30, 2026 10-Q May 6, 2025
Ourania "Nia" Tatsis
EVP, Chief Regulatory and Quality Officer
Adopted 10b5-1 plan Nov 22, 2024 up to 11,270 Oct 31, 2025 10-K Feb 13, 2025
Charles F. Wagner, Jr
EVP, Chief Financial Officer
Adopted 10b5-1 plan Aug 8, 2024 up to 6,298 Aug 1, 2025 10-Q Nov 5, 2024
David Altshuler
EVP, Chief Scientific Officer
Adopted 10b5-1 plan Aug 8, 2024 up to 30,510 Aug 1, 2025 10-Q Nov 5, 2024
Kristen Ambrose
SVP, Chief Accounting Officer
Adopted 10b5-1 plan Aug 8, 2024 up to 4,914 Aug 1, 2025 10-Q Nov 5, 2024
Jeffrey Leiden
Executive Chairman
Adopted 10b5-1 plan May 10, 2024 up to 11,355 Aug 31, 2025 10-Q Aug 2, 2024
Sangeeta Bhatia
Director
Adopted 10b5-1 plan May 9, 2024 up to 2,339 May 9, 2025 10-Q Aug 2, 2024
Ourania "Nia" Tatsis
EVP, Chief Regulatory and Quality Officer
Adopted 10b5-1 plan Feb 29, 2024 up to 9,484 427 days 10-Q May 7, 2024
Carmen Bozic
EVP, Global Medicines Development and Medical Affairs, and Chief Medical Officer
Adopted 10b5-1 plan Feb 27, 2024 up to 13,680 339 days 10-Q May 7, 2024
Charles F. Wagner, Jr.
EVP, Chief Financial Officer
Adopted 10b5-1 plan Feb 26, 2024 up to 6,500 340 days 10-Q May 7, 2024
E. Morrow "Morrey" Atkinson, III
EVP, Chief Technical Operations Officer, Head of Biopharmaceutical Sciences and Manufacturing Operations
Adopted 10b5-1 plan Feb 22, 2024 up to 25,290 372 days 10-Q May 7, 2024
Jonathan Biller
EVP, Chief Legal Officer
Adopted 10b5-1 plan Feb 13, 2024 up to 9,825 442 days 10-Q May 7, 2024
Bruce Sachs
Director
Adopted 10b5-1 plan Feb 12, 2024 up to 12,368 382 days 10-Q May 7, 2024
Reshma Kewalramani
Chief Executive Officer and President
Adopted 10b5-1 plan Feb 7, 2024 up to 96,388 468 days 10-Q May 7, 2024
Bastiano Sanna
EVP, Chief of Cell and Genetic Therapies
Adopted 10b5-1 plan Aug 25, 2023 up to 32,833 350 days 10-Q Nov 7, 2023
E. Morrow “Morrey” Atkinson III
EVP, Chief Technical Operations Officer, Head of Biopharmaceutical Sciences and Manufacturing Operations
Adopted 10b5-1 plan Aug 22, 2023 up to 9,224 252 days 10-Q Nov 7, 2023
Charles F. Wagner, Jr.
EVP, Chief Financial Officer
Adopted 10b5-1 plan Aug 18, 2023 up to 6,000 357 days 10-Q Nov 7, 2023
Reshma Kewalramani
President, Chief Executive Officer and Director
Adopted 10b5-1 plan Aug 11, 2023 up to 27,330 370 days 10-Q Nov 7, 2023
Jeffrey M. Leiden
Executive Chairman
Adopted 10b5-1 plan Aug 4, 2023 up to 40,454 650 days 10-Q Nov 7, 2023
Carmen Bozic
EVP, Global Medicines Development and Medical Affairs, Chief Medical Officer
Adopted 10b5-1 plan May 30, 2023 up to 33,905 246 days 10-Q Aug 2, 2023
David Altshuler
EVP, Global Research and Chief Scientific Officer
Adopted 10b5-1 plan May 10, 2023 up to 32,896 373 days 10-Q Aug 2, 2023
Sangeeta Bhatia
Director
Adopted 10b5-1 plan May 10, 2023 up to 1,194 366 days 10-Q Aug 2, 2023
Amit Sachdev
EVP, Chief Patient Officer
Adopted 10b5-1 plan May 9, 2023 up to 40,128 377 days 10-Q Aug 2, 2023
Ourania Tatsis
EVP, Chief Regulatory and Quality Officer
Adopted 10b5-1 plan May 9, 2023 up to 11,783 358 days 10-Q Aug 2, 2023
Terrence Kearney
Director
Adopted 10b5-1 plan May 9, 2023 up to 10,000 234 days 10-Q Aug 2, 2023

From the XBRL of the company's 10-Qs and 10-Ks (Regulation S-K Item 408, reported since 2023): 15 filings checked since May 2, 2023.

Form 144 notices of planned sales

FiledSellerSharesValueShares came from10b5-1 planForm 4 sales after
Nov 6, 2026 Kewalramani Reshma
Officer, Director
11,866 $6,307,135 ESPP Purchase; Restricted Stock Vesting adopted Aug 5, 2026 none found
Aug 27, 2026 Bruce I. Sachs
Director
1,210 $662,536 Acquired as a gift none given none found
Jul 2, 2026 Tatsis Ourania
Officer
1,500 $787,485 Restricted Stock Vesting adopted Aug 21, 2025 1,500 shares from Jul 2, 2026
Jul 2, 2026 McKechnie Duncan
Officer
1,541 $799,779 Restricted Stock Vesting adopted Nov 25, 2025 1,541 shares from Jul 2, 2026
Jul 1, 2026 Liu Joy
Officer
828 $416,244 Restricted Stock Vesting adopted Nov 25, 2025 828 shares from Jul 1, 2026
Jun 26, 2026 Bozic Carmen
Officer
596 $287,570 Restricted Stock Vesting adopted Nov 20, 2025 596 shares from Jun 26, 2026
Jun 18, 2026 Bozic Carmen
Officer
1,020 $471,413 Restricted Stock Vesting adopted Nov 20, 2025 1,616 shares from Jun 18, 2026
Jun 15, 2026 Bozic Carmen
Officer
4,062 $1,827,900 Restricted Stock Vesting adopted Nov 20, 2025 5,678 shares from Jun 15, 2026
Jun 5, 2026 Bozic Carmen
Officer
1,745 $785,250 Restricted Stock Vesting adopted Nov 20, 2025 7,423 shares from Jun 5, 2026
Jun 1, 2026 Liu Joy
Officer
828 $364,245 Restricted Stock Vesting adopted Nov 25, 2025 1,656 shares from Jun 1, 2026
May 29, 2026 Bozic Carmen
Officer
1,974 $888,300 Restricted Stock Vesting adopted Nov 20, 2025 9,397 shares from May 29, 2026
May 15, 2026 Bozic Carmen
Officer
1,354 $613,971 Restricted Stock Vesting adopted Nov 20, 2025 5,073 shares from May 15, 2026
May 15, 2026 Bunnage Mark E.
Officer
33 $14,964 ESPP Purchase adopted Nov 26, 2025 33 shares from May 15, 2026
May 12, 2026 Bozic Carmen
Officer
6,988 $3,144,600 Restricted Stock Vesting adopted Nov 20, 2025 12,061 shares from May 12, 2026
May 6, 2026 Biller Jonathan
Officer
5,193 $2,203,149 Restricted Stock Vesting none given none found
May 4, 2026 Bhatia Sangeeta N.
Director
318 $134,746 Restricted Stock Vesting adopted May 27, 2025 318 shares from May 4, 2026
May 1, 2026 Liu Joy
Officer
1,104 $469,222 Restricted Stock Vesting adopted Nov 25, 2025 1,104 shares from May 1, 2026
Apr 1, 2026 Liu Joy
Officer
978 $439,288 Restricted Stock Vesting adopted Nov 25, 2025 1,104 shares from May 1, 2026
Mar 27, 2026 Bozic Carmen
Officer
2,329 $1,050,263 Restricted Stock Vesting adopted Nov 20, 2025 none found
Mar 13, 2026 Bozic Carmen
Officer
2,329 $1,122,089 Restricted Stock Vesting adopted Nov 20, 2025 none found
Mar 11, 2026 McKechnie Duncan
Officer
2,633 $1,312,340 Restricted Stock Vesting adopted Nov 25, 2025 none found
Mar 4, 2026 McKechnie Duncan
Officer
2,437 $1,158,306 Restricted Stock Vesting adopted Nov 25, 2025 none found
Mar 2, 2026 Liu Joy
Officer
892 $442,396 Restricted Stock Vesting adopted Nov 25, 2025 none found
Feb 27, 2026 Kewalramani Reshma
Officer, Director
40,000 $19,738,905 Restricted Stock Vesting adopted Nov 17, 2025 none found
Feb 27, 2026 Bozic Carmen
Officer
2,329 $1,118,642 Restricted Stock Vesting adopted Nov 20, 2025 none found
Feb 25, 2026 McKechnie Duncan
Officer
4,910 $2,394,365 ESPP Purchase; Restricted Stock Vesting adopted Nov 25, 2025 none found
Feb 25, 2026 Tatsis Ourania
Officer
260 $126,451 Restricted Stock Vesting adopted Aug 21, 2025 none found
Feb 25, 2026 Bunnage Mark E.
Officer
620 $301,537 Restricted Stock Vesting adopted Nov 26, 2025 none found
Feb 25, 2026 Atkinson Edward Morrow III
Officer
668 $324,882 Restricted Stock Vesting adopted Aug 11, 2025 none found
Feb 25, 2026 Sachdev Amit
Officer
1,846 $897,802 Restricted Stock Vesting adopted Nov 18, 2025 none found
Feb 25, 2026 Biller Jonathan
Officer
945 $459,601 Restricted Stock Vesting adopted Feb 24, 2025 none found
Feb 19, 2026 Sachdev Amit
Officer
58,613 $27,479,576 Option Granted - 02/06/2018; Option Granted - 02/06/2019; Restricted Stock Vesting adopted Nov 18, 2025 none found
Feb 18, 2026 Tatsis Ourania
Officer
368 $174,314 Restricted Stock Vesting adopted Aug 21, 2025 none found
Feb 18, 2026 Biller Jonathan
Officer
1,244 $589,258 Restricted Stock Vesting adopted Feb 24, 2025 none found
Feb 18, 2026 Bunnage Mark E.
Officer
1,182 $559,890 Restricted Stock Vesting adopted Nov 26, 2025 none found
Feb 18, 2026 Atkinson Edward Morrow III
Officer
817 $386,997 Restricted Stock Vesting adopted Aug 11, 2025 none found
Feb 17, 2026 Bunnage Mark E.
Officer
2,437 $1,192,814 Restricted Stock Vesting adopted Nov 26, 2025 none found
Feb 17, 2026 Tatsis Ourania
Officer
609 $298,081 Restricted Stock Vesting adopted Aug 21, 2025 none found
Feb 17, 2026 Biller Jonathan
Officer
2,476 $1,211,903 Restricted Stock Vesting adopted Feb 24, 2025 none found
Feb 17, 2026 Atkinson Edward Morrow III
Officer
2,031 $994,093 Restricted Stock Vesting adopted Aug 11, 2025 none found
Feb 13, 2026 Biller Jonathan
Officer
988 $493,012 Restricted Stock Vesting adopted Feb 24, 2025 none found
Feb 13, 2026 Bhatia Sangeeta N.
Director
266 $133,000 Restricted Stock Vesting adopted May 27, 2025 none found
Feb 13, 2026 Tatsis Ourania
Officer
1,500 $749,992 Restricted Stock Vesting adopted Aug 21, 2025 none found
Feb 11, 2026 Biller Jonathan
Officer
1,925 $886,328 Restricted Stock Vesting adopted Feb 24, 2025 none found
Feb 11, 2026 Atkinson Edward Morrow III
Officer
1,751 $806,213 Restricted Stock Vesting adopted Aug 11, 2025 none found
Feb 11, 2026 Bunnage Mark E.
Officer
2,021 $930,529 Restricted Stock Vesting adopted Nov 26, 2025 none found
Feb 11, 2026 Tatsis Ourania
Officer
466 $214,560 Restricted Stock Vesting adopted Aug 21, 2025 none found
Jan 7, 2026 Tatsis Ourania
Officer
4,500 $2,137,455 ESPP Purchase; Restricted Stock Vesting adopted Aug 21, 2025 none found
Jan 6, 2026 WAGNER CHARLES F JR
Officer
9,532 $4,394,252 Options Granted - 04/10/2019 adopted May 9, 2025 none found
Dec 3, 2025 WAGNER CHARLES F JR
Officer
7,000 $3,227,000 Restricted Stock Vesting adopted May 9, 2025 none found
Dec 3, 2025 WAGNER CHARLES F JR
Officer
7,000 $3,157,000 Restricted Stock Vesting adopted May 9, 2025 none found
Dec 3, 2025 Tatsis Ourania
Officer
4,500 $2,024,955 ESPP Purchase; Restricted Stock Vesting adopted Aug 21, 2025 none found
Dec 3, 2025 Biller Jonathan
Officer
347 $155,803 Restricted Stock Vesting adopted Feb 24, 2025 none found
Dec 3, 2025 JEFFREY M LEIDEN
Director, Officer
63,781 $27,626,740 Exercise of Stock Options adopted Aug 6, 2025 none found
Nov 20, 2025 CARNEY LLOYD
Director
800 $341,088 Stock Award none given none found
Nov 17, 2025 Atkinson Edward Morrow III
Officer
2,500 $1,086,450 Restricted Stock Vesting adopted Aug 11, 2025 none found
Nov 14, 2025 JEFFREY M LEIDEN
Director, Officer
53,604 $23,292,010 Exercise of Stock Options adopted Aug 6, 2025 none found
Nov 13, 2025 JEFFREY M LEIDEN
Director, Officer
19,688 $8,548,333 Exercise of Stock Options adopted Aug 6, 2025 none found

From the Form 144 XML filed with the SEC, since Nov 13, 2025. The value is the seller's estimate on the notice. "Form 4 sales after" matches the seller's Form 4 sales in the 30 days after the notice, by name; Form 4s go back 180 days.

Work on VRTX in a spreadsheet: Excel workbook (a sheet per section, ten years by column, charts, links to the filings) · CSV. For a Google Sheet that stays up to date, paste =IMPORTDATA("https://tickdelta.com/company/VRTX/export.csv") into a cell.